AcSDKP ELISA Kits

N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP) is an endogenous tetrapeptide that plays a significant role in hematopoiesis by regulating the proliferation of hematopoietic stem cells. It is also involved in cardiovascular physiology and has been studied for its potential therapeutic applications. AcSDKP is primarily degraded by angiotensin-converting enzyme (ACE), making its measurement valuable in research related to ACE inhibition and associated physiological processes.

Key Features:

• Sensitivity and Specificity: Designed to detect low concentrations of AcSDKP with high specificity, minimizing cross-reactivity with similar peptides.
• Assay Range: Typically, these kits offer a detection range suitable for physiological levels of AcSDKP, for example, 0.235 ng/mL to 15 ng/mL, with sensitivities around 0.058 ng/mL. Cusbio
• Sample Types: Validated for use with various sample matrices, including serum, plasma, and tissue homogenates, providing versatility for different research needs.
• Assay Time: The total assay duration varies but generally ranges from 1 to 5 hours, facilitating efficient processing of multiple samples.

Applications:

• Cardiovascular Research: AcSDKP is involved in cardiovascular physiology, and its levels are influenced by ACE activity. Measuring AcSDKP can provide insights into the effects of ACE inhibitors and the regulation of blood pressure.
• Hematopoiesis Studies: Due to its role in regulating hematopoietic stem cell proliferation, AcSDKP measurement is valuable in studies of bone marrow function and disorders.
• Pharmacological Research: Evaluating the impact of drugs, particularly ACE inhibitors, on AcSDKP levels can help understand their mechanisms and therapeutic effects.

By providing accurate quantification of AcSDKP levels, these ELISA kits are invaluable tools in biomedical research, particularly in studies related to cardiovascular health, hematopoiesis, and the pharmacodynamics of ACE inhibitors.