C(CST3) ELISA Kits

Cystatin C (CST3) is a cysteine protease inhibitor that is expressed in all nucleated cells and is widely used as a biomarker for kidney function, cardiovascular disease, and neurodegenerative disorders. Unlike other renal markers, Cystatin C is less affected by muscle mass, making it a reliable indicator of glomerular filtration rate (GFR). CST3 ELISA Kits are designed to measure Cystatin C levels in biological samples, such as serum, plasma, urine, and cerebrospinal fluid, offering high sensitivity and specificity for various research and clinical applications.

Content of CST3 ELISA Kits

CST3 ELISA Kits typically include:

• Pre-coated ELISA Plate: A 96-well plate pre-coated with anti-Cystatin C antibodies, ensuring specific and efficient capture of CST3 in samples.
• Standards and Controls: Known concentrations of CST3 for establishing a standard curve, enabling accurate quantification across a wide range of sample concentrations.
• Detection Antibody: A biotinylated or enzyme-conjugated antibody specific to Cystatin C, which binds to the captured CST3, allowing for signal amplification for precise quantification.
• Substrate Solution: A colorimetric substrate like TMB (3,3',5,5'-Tetramethylbenzidine) that produces a measurable signal proportional to CST3 concentration in the sample.

Application of CST3 ELISA Kits

CST3 ELISA Kits are used in a variety of research areas, including:

• Kidney Function Assessment: CST3 is a reliable biomarker for estimating GFR, making it an important marker for assessing renal function, especially in chronic kidney disease (CKD) and acute kidney injury (AKI). CST3 levels help monitor disease progression and evaluate therapeutic responses.
• Cardiovascular Disease Research: Elevated Cystatin C levels are associated with cardiovascular disease risks, including heart failure and atherosclerosis. CST3 ELISA Kits allow for the quantification of CST3 as a potential indicator of cardiovascular events and outcomes.
• Inflammatory and Metabolic Disorders: CST3 levels can indicate inflammation and have been observed in conditions like rheumatoid arthritis and obesity-related metabolic syndrome. Measuring CST3 supports studies on inflammation and immune response in chronic inflammatory diseases.

Overall, CST3 ELISA Kits provide accurate, quantitative data essential for understanding kidney health, cardiovascular risk, and neuroinflammatory processes, supporting advancements in diagnostics and therapeutic research.