CSF2 ELISA Kits
CSF2 ELISA Kits are specialized assay systems designed to detect and quantify granulocyte-macrophage colony-stimulating factor (GM-CSF), a cytokine involved in immune regulation, inflammation, and hematopoiesis. The kits utilize a high-affinity sandwich ELISA technique, providing reliable, reproducible, and highly sensitive measurements in various biological samples such as serum, plasma, cell culture supernatants, and tissue lysates.
Key Features:
- High Sensitivity and Specificity: Detects CSF2 at picogram levels with minimal cross-reactivity to other cytokines.
- Wide Sample Range: Compatible with human, mouse, and other species, depending on the kit design.
- Ease of Use: Pre-coated plates, biotinylated detection antibodies, and ready-to-use reagents streamline the assay process.
- Rapid Protocol: Generates results within 2-3 hours with high throughput capabilities.
- Versatile Output: Colorimetric or chemiluminescent detection for flexible readout options.
Applications:
- Clinical Diagnostics:
- Autoimmune and Inflammatory Diseases: Measure GM-CSF levels in conditions such as rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis to monitor disease activity and therapeutic response.
- Cancer Biomarker: Assess GM-CSF in tumor microenvironments for its role in cancer progression and as a potential therapeutic target.
- Infectious Disease: Monitor cytokine dysregulation in sepsis or chronic infections.
- Drug Development:
- Therapeutics: Evaluate the efficacy of GM-CSF-targeted drugs or biologics, such as monoclonal antibodies and receptor inhibitors.
- Toxicology Studies: Monitor cytokine release in preclinical and clinical trials, particularly for immunotherapy agents.
- Immunological Research:
- Cell Differentiation: Investigate GM-CSF’s role in macrophage and dendritic cell activation and its influence on T-cell responses.
- Cytokine Networks: Study GM-CSF signaling pathways and interactions with other immune mediators.
- Hematopoiesis: Analyze its contribution to granulocyte and macrophage lineage differentiation.
CSF2 ELISA Kits are indispensable in both basic research and clinical studies, offering precision and consistency in cytokine measurement, essential for advancing diagnostics, therapeutic development, and understanding immune system dynamics.
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