FcαRI ELISA Kits

The FcαRI ELISA Kit is a specialized immunoassay designed to detect and quantify Fc alpha receptor I (FcαRI, also known as CD89) in various sample types, including serum, plasma, and cell culture supernatants. FcαRI is a receptor expressed on the surface of immune cells, such as neutrophils, monocytes, and macrophages, and plays a critical role in immune responses through its binding to the Fc region of IgA antibodies. The kit utilizes highly specific antibodies to ensure selective and accurate measurement of FcαRI levels.

Content of FcαRI ELISA Kit

The kit includes pre-coated microtiter plates with antibodies specific to FcαRI, along with necessary reagents for detection, such as a biotinylated detection antibody, streptavidin-HRP conjugate, and a TMB substrate solution for color development. Standard controls are provided to establish a quantifiable range of FcαRI concentrations. The kit components are optimized for efficient binding and sensitivity, ensuring accurate results even at low FcαRI concentrations.

Application of FcαRI ELISA Kit

The FcαRI ELISA Kit is a valuable tool for researchers studying immunological responses, inflammation, and infectious diseases. Applications include:

• Quantifying FcαRI Expression: Researchers can use the kit to measure FcαRI levels in different sample types, allowing for insights into receptor expression patterns across various disease states, such as autoimmune disorders or infections where IgA-mediated immunity is relevant.
• Pathogenesis Studies: Given FcαRI’s role in mediating IgA-dependent immune responses, this ELISA kit can support studies on FcαRI-related signaling pathways and cellular activation, which are critical in conditions involving mucosal immunity or pathogen invasion.
• Immunotherapy Research: As FcαRI is involved in ADCC (antibody-dependent cellular cytotoxicity), this kit can aid in assessing the impact of therapeutic agents that modulate FcαRI function or IgA interactions, potentially contributing to the development of IgA-based immunotherapies.

This FcαRI ELISA Kit provides precise and reproducible quantification, supporting advanced immunological research with reliable results.