GSTA ELISA Kits
GSTA (Glutathione S-Transferase Alpha) ELISA Kits are specialized assay systems designed for the quantitative measurement of GSTA proteins in various biological samples such as serum, plasma, cell lysates, and tissue homogenates. GSTA proteins are part of the glutathione S-transferase family, which play a crucial role in detoxification processes by catalyzing the conjugation of glutathione to a variety of endogenous and exogenous electrophilic compounds.
Content:
GSTA ELISA Kits typically employ a sandwich-based enzyme-linked immunosorbent assay approach. The kits are pre-coated with high-affinity antibodies specific to the GSTA isoforms, ensuring precise and reliable quantification. Key components of the kit include:
- Pre-coated 96-well plates with capture antibodies.
- Detection antibodies specific to GSTA.
- Standards and control samples.
- HRP-conjugated reagents.
Application of GSTA ELISA Kits:
GSTA ELISA Kits are widely used in research and clinical studies to assess the level of oxidative stress and detoxification capacity within tissues and cells. Researchers rely on GSTA ELISA Kits for:
- Pharmacokinetics and Toxicology Studies: To measure the hepatic response to drug treatments and evaluate liver injury biomarkers.
- Pathophysiological Research: For investigating conditions characterized by altered oxidative metabolism or increased exposure to toxic compounds.
- Clinical Diagnostics: In potential diagnostic assessments related to liver function and detoxification impairments.
This technical capability allows for the elucidation of cellular defense mechanisms and the role of GSTA in various biochemical pathways involved in cellular protection and detoxification.
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