HAVCR ELISA Kits

HAVCR (Hepatitis A Virus Cellular Receptor), also known as TIM-1 (T-cell immunoglobulin and mucin-domain containing-1), ELISA kits are immunoassays designed for the quantitative detection of HAVCR protein in biological samples such as serum, plasma, and cell lysates. HAVCR is a multifunctional protein involved in immune regulation, pathogen recognition, and kidney function. It is notably associated with viral entry for hepatitis A and plays a role in modulating immune responses. HAVCR/TIM-1 is also implicated in various diseases, including immune disorders, kidney disease, and cancer.

Content of HAVCR ELISA Kits: HAVCR ELISA kits typically include:

• A 96-well microplate pre-coated with specific capture antibodies for HAVCR/TIM-1.
• Recombinant HAVCR protein standards for generating a standard curve.
• Detection antibodies conjugated with an enzyme, such as HRP (Horseradish Peroxidase), for signal amplification.
• Substrate solution (e.g., TMB – 3,3',5,5'-Tetramethylbenzidine) for color development.
• Stop solution to halt the enzymatic reaction.
• Sample and assay diluents, wash buffers, and detailed instructions for performing the assay and sample preparation.

Application of HAVCR ELISA Kits: HAVCR ELISA kits are utilized in a variety of research and clinical applications, including:

• Viral infection studies: Measuring HAVCR levels to understand its role as a receptor for hepatitis A virus and its involvement in viral entry and immune response modulation.
• Immunology research: Investigating HAVCR's function in T-cell activation and regulation, which is relevant for autoimmune and allergic conditions.
• Kidney disease research: Studying HAVCR/TIM-1 expression in kidney tissues to evaluate its association with acute kidney injury (AKI) and chronic kidney disease (CKD).
• Cancer research: Analyzing the role of HAVCR in tumor progression and immune evasion, particularly in the context of cancers where TIM-1 expression is altered.
• Transplantation studies: Evaluating HAVCR levels to assess potential markers for graft rejection or immune response regulation post-transplant.
• Drug development: Screening for potential inhibitors or modulators of HAVCR for therapeutic applications in immune-related diseases and viral infections.

HAVCR ELISA kits are valuable tools for researchers studying immune regulation, viral infections, and kidney function, providing critical data for understanding the role of HAVCR/TIM-1 in health and disease.