MPO-ANCA ELISA Kits
Myeloperoxidase (MPO) is an enzyme predominantly found in neutrophil granules, playing a crucial role in the body's defense mechanisms. Autoantibodies targeting MPO, known as MPO-ANCA (anti-neutrophil cytoplasmic antibodies), are significant biomarkers in diagnosing certain autoimmune vasculitides, including microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis. The detection and quantification of these autoantibodies are commonly performed using Enzyme-Linked Immunosorbent Assay (ELISA) kits.
Available MPO-ANCA ELISA Kits:
- Anti-MPO (p-ANCA) ELISA by DiaMetra:
- Description: This indirect solid-phase enzyme immunoassay quantitatively measures IgG class autoantibodies against MPO in human serum or plasma. It is intended for in vitro diagnostic use as an aid in diagnosing certain autoimmune vasculitides.
- Applications: Applicable in clinical research and diagnostics related to autoimmune vasculitides.
- Human Myeloperoxidase ELISA Kit (MPO) by Abcam:
- Description: This in vitro ELISA kit is designed for the accurate quantitative measurement of MPO in cell culture supernatants, cell lysates, tissue homogenates, serum, plasma, saliva, and urine.
- Applications: Suitable for research in oxidative stress, inflammation, and related fields.
Applications of MPO-ANCA ELISA Kits:
- Autoimmune Disease Research: These kits are instrumental in studying autoimmune vasculitides, aiding in understanding disease mechanisms and progression.
- Clinical Diagnostics: They serve as valuable tools in diagnosing conditions associated with MPO-ANCA, such as microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis.
- Therapeutic Monitoring: Quantifying MPO-ANCA levels can assist in monitoring treatment efficacy and disease remission status.
When selecting an MPO-ANCA ELISA kit, consider factors such as sample type compatibility, assay sensitivity, specificity, and the intended application to ensure optimal results.
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