MyD88 ELISA Kits
Myeloid differentiation primary response protein 88 (MyD88) is a pivotal adaptor protein in the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways, playing a crucial role in the innate immune response. Quantifying MyD88 levels is essential for understanding its involvement in various physiological and pathological processes, including inflammation, immune responses, and certain cancers.
Key Features:
- Specificity: Utilize antibodies that selectively bind to MyD88, minimizing cross-reactivity with other proteins.
- Sensitivity: Capable of detecting low concentrations of MyD88, with detection limits often in the picogram per milliliter (pg/mL) range.
- Sample Compatibility: Validated for use with various sample types across multiple species, facilitating broad applicability in research.
Applications:
- Immunological Research: Investigating the role of MyD88 in innate immune signaling pathways and its involvement in inflammatory responses.
- Disease Studies: Assessing MyD88 expression levels in conditions such as autoimmune diseases, infectious diseases, and cancers.
- Drug Development: Evaluating the impact of therapeutic agents targeting TLR/IL-1R signaling pathways on MyD88 expression.
Examples of MyD88 ELISA Kits:
- Human MyD88 ELISA Kit (ab171341): Designed for the quantitative detection of human MyD88 in cell culture supernatants, with a detection range of 156–10,000 pg/mL and a sensitivity of less than 10 pg/mL.
- Human MyD88 ELISA Kit (ABIN1672854): A sandwich ELISA kit for measuring human MyD88 in cell culture supernatants, with a detection range of 312–20,000 pg/mL and a sensitivity of less than 10 pg/mL.
- Human MyD88 ELISA Kit (OKBB00470): Utilizes a monoclonal antibody from mouse specific for MyD88, with a detection range of 312–20,000 pg/mL and a sensitivity of less than 10 pg/mL.
These MyD88 ELISA kits are indispensable tools for researchers aiming to elucidate the role of MyD88 in health and disease, providing reliable and reproducible data essential for advancing our understanding of immune signaling processes.
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