NAG ELISA Kits

N-acetyl-β-D-glucosaminidase (NAG) ELISA Kits are specialized immunoassays designed to quantify NAG, a lysosomal enzyme involved in the breakdown of glycoproteins, glycolipids, and glycosaminoglycans. NAG is particularly abundant in renal tubular cells and is often released into the urine following kidney damage, making it a valuable biomarker for renal injury and dysfunction.

Content:

NAG ELISA Kits typically include highly specific antibodies against NAG, pre-coated plates, detection reagents, calibration standards, wash buffers, and substrates. These kits use a sandwich ELISA format, providing a highly sensitive and specific assay for detecting NAG in samples such as urine, serum, plasma, and tissue homogenates. The kits are optimized for accuracy and reproducibility, allowing researchers to monitor NAG levels in a wide range of biological contexts.

Applications:

• Diabetes and Hypertension Research: NAG levels are elevated in diabetic nephropathy and hypertensive nephropathy, where kidney function is compromised by high blood glucose or blood pressure. NAG ELISA kits enable researchers to investigate how diabetes and hypertension affect kidney health, monitor disease progression, and study the impact of treatments that protect against kidney damage in these conditions.
• Organ Transplantation Monitoring: NAG levels can be a marker of kidney transplant health, as elevated NAG in urine may signal early rejection or kidney injury in transplant recipients. NAG ELISA kits are used in transplant research and clinical monitoring to help identify potential complications and guide immunosuppressive therapy adjustments.
• General Inflammation and Immune Response: While primarily associated with kidney health, NAG is also involved in inflammatory responses. NAG ELISA kits may be used in research examining inflammation-related diseases, where elevated NAG levels could reflect cellular injury or immune activity in tissues beyond the kidney.

NAG ELISA Kits provide a reliable and precise method for quantifying NAG, making them essential tools in renal health research, toxicology, and beyond. By accurately measuring this important biomarker, NAG ELISA Kits facilitate early detection of kidney injury, enabling researchers and clinicians to better understand, prevent, and treat conditions affecting renal function.