OR5 ELISA Kits

OR5 (Olfactory Receptor 5) ELISA Kits are advanced immunoassays designed for the quantitative measurement of OR5 proteins in biological samples, including cell lysates and tissue homogenates. OR5 belongs to the family of G-protein-coupled receptors (GPCRs) and is primarily associated with olfactory signal transduction. These receptors are known for their role in detecting odorants and initiating the sense of smell. Beyond their classical roles in olfaction, certain olfactory receptors, including OR5 variants, have been implicated in various cellular functions and physiological processes.

Content:

OR5 ELISA Kits are typically based on a sandwich enzyme-linked immunosorbent assay approach, ensuring specific and sensitive detection. The assay involves the following steps:

• Capture Phase: The wells of the ELISA plate are pre-coated with specific capture antibodies that bind to OR5 proteins present in the sample.
• Sample Binding: Biological samples containing OR5 proteins are incubated in the coated wells, allowing binding to the immobilized antibodies.
• Detection Phase: A detection antibody specific to a different epitope on the OR5 protein is added, forming a sandwich complex.
• Quantification: The color intensity, directly proportional to the concentration of OR5 protein, is measured at a specific wavelength using an ELISA plate reader.

Application of OR5 ELISA Kits:

OR5 ELISA Kits are useful in various research fields, including:

• Olfactory and Sensory Biology: Studying the expression and regulation of OR5 proteins in tissues involved in the sense of smell and their role in signal transduction pathways.
• Cancer Research: Emerging studies suggest that certain olfactory receptors, including OR5, may be expressed in non-olfactory tissues and could play roles in cancer cell proliferation, migration, and invasion. Quantifying OR5 expression helps in exploring potential links between OR5 and tumor biology.
• Neurobiology: Investigating the potential roles of olfactory receptors in brain function and their involvement in non-sensory processes such as neurotransmission and neuroplasticity.

The high sensitivity and specificity of OR5 ELISA Kits make them essential tools for studying olfactory receptors and their potential roles in non-olfactory systems, contributing to a better understanding of cellular signaling and disease mechanisms.