PLACE ELISA Kits

PLAC ELISA kits are specialized immunoassays used to measure the levels of placental-associated proteins, such as Placental Growth Factor (PlGF) or other related biomarkers, in various biological samples including serum, plasma, and tissue extracts. PlGF is a member of the vascular endothelial growth factor (VEGF) family and plays a crucial role in angiogenesis and placental development. The measurement of these proteins is valuable in research areas related to pregnancy, preeclampsia, and cardiovascular health.

Content: PLAC ELISA kits typically use a sandwich ELISA format for detecting specific placental-associated proteins with high sensitivity and specificity. Common components of these kits include:

• Standards and controls for generating a standard curve for precise quantification.
• Biotinylated detection antibody for binding to the captured PLAC protein.
• Enzyme conjugate (e.g., Streptavidin-HRP) for signal enhancement.
• TMB substrate solution, which produces a measurable color change upon enzymatic reaction.
• Stop solution to terminate the reaction.
• Wash buffers and assay diluents for assay consistency and reproducibility.

Applications: PLAC ELISA kits are used in various research and clinical studies, including:

• Obstetric Research: Monitoring PlGF levels as an indicator of placental health and function. It is particularly significant in studying pregnancy complications such as preeclampsia, where altered PlGF levels are observed.
• Angiogenesis Studies: Investigating the role of placental-associated growth factors in blood vessel formation and their contributions to different pathological and physiological conditions.
• Cardiovascular Health: Examining the involvement of PlGF and related markers in cardiovascular diseases, as elevated levels are linked to certain cardiac conditions.
• Cancer Research: Studying the expression of placental proteins in tumors and their potential role in cancer progression and metastasis.

PLAC ELISA kits provide a reliable method for quantifying placental growth factors and related biomarkers in various samples. They are crucial for research in obstetrics, angiogenesis, and cardiovascular health, offering valuable insights into the mechanisms underlying normal and pathological conditions. The data obtained from these assays contribute to better understanding, diagnosis, and treatment development in fields related to pregnancy, cardiovascular diseases, and cancer.