PLXNB ELISA Kits

PLXNB (Plexin B) ELISA kits are immunoassays designed for the quantitative detection of Plexin B proteins in biological samples such as serum, plasma, and tissue lysates. Plexin B proteins are part of the plexin family, which serves as receptors for semaphorins and plays significant roles in cellular processes such as cell migration, axonal guidance, and angiogenesis. They are involved in signaling pathways that regulate cytoskeletal dynamics and are associated with cancer progression, neurodevelopment, and immune responses.

Content of PLXNB ELISA Kits: PLXNB ELISA kits typically include:

• A 96-well microplate pre-coated with capture antibodies specific to Plexin B proteins.
• Recombinant PLXNB protein standards for generating a standard curve.
• Detection antibodies conjugated to an enzyme, such as HRP (Horseradish Peroxidase), for colorimetric signal detection.
• Substrate solution (e.g., TMB – 3,3',5,5'-Tetramethylbenzidine) for color development.
• Stop solution to terminate the enzymatic reaction.
• Sample and assay diluents, wash buffers, and comprehensive instructions for assay setup and sample handling.

Application of PLXNB ELISA Kits: PLXNB ELISA kits are used in various research and clinical applications, including:

• Cancer research: Measuring PLXNB expression to understand its role in tumor growth, metastasis, and angiogenesis. Plexin B proteins can modulate signaling pathways that influence cancer cell behavior.
• Neuroscience: Studying the function of PLXNB in neuronal development, axonal guidance, and synaptic plasticity, which are essential for understanding neurodevelopmental and neurodegenerative conditions.
• Angiogenesis research: Investigating the role of PLXNB in blood vessel formation and its interactions with other signaling molecules involved in vascular biology.
• Immune response studies: Analyzing PLXNB’s role in immune cell regulation and response, as plexins can influence immune cell migration and activity.
• Cell migration and cytoskeleton research: Understanding how PLXNB impacts cellular movement and structural organization, which is critical for developmental biology and wound healing research.
• Drug development: Evaluating potential therapies that target PLXNB signaling pathways for the treatment of cancers and other diseases linked to its expression and activity.

PLXNB ELISA kits are essential tools for researchers investigating the roles of Plexin B in various cellular and pathological processes, contributing to a deeper understanding of its involvement in development, disease progression, and potential therapeutic strategies.