PPP1R1B ELISA Kits

Protein Phosphatase 1 Regulatory Subunit 1B (PPP1R1B), also known as DARPP-32 (Dopamine- and cAMP-Regulated Phosphoprotein of 32 kDa), is a pivotal protein in dopaminergic signaling pathways, particularly within the central nervous system. It functions as a potent inhibitor of protein phosphatase-1 (PP1), thereby modulating various physiological processes, including synaptic plasticity and neurotransmission. 

Available PPP1R1B ELISA Kits:

• Human PPP1R1B ELISA Kit by ELK Biotechnology
  • Features: Utilizes a sandwich enzyme immunoassay technique for the detection of human PPP1R1B in tissue homogenates, cell lysates, and other biological fluids.
  • Detection Range: 0.16–10 ng/mL
  • Sensitivity: 0.054 ng/mL
  • Applications: Applicable for measuring PPP1R1B levels in various human samples, aiding in studies related to metabolic pathways.
• Human PPP1R1B ELISA Kit by Thomas Scientific
  • Features: High-quality and validated sandwich ELISA kit with reactivity against human samples.
  • Detection Range: 0.156–10 µg/mL
  • Sensitivity: 0.072 µg/mL
  • Applications: Suitable for research involving human PPP1R1B expression and its role in disease mechanisms.

Applications of PPP1R1B ELISA Kits:

• Neuroscience Research: Investigating the role of PPP1R1B in dopaminergic signaling, synaptic plasticity, and its implications in neurological disorders such as schizophrenia and Parkinson's disease.
• Pharmacological Studies: Evaluating the effects of drugs targeting dopaminergic pathways on PPP1R1B expression and activity.
• Molecular Biology: Studying the regulatory mechanisms controlling PPP1R1B expression and its interaction with other signaling molecules.

When selecting a PPP1R1B ELISA kit, consider factors such as sample type compatibility, sensitivity, detection range, and the specific requirements of your research. Consulting the manufacturer's datasheet and technical support can provide additional guidance to ensure optimal results.