PRDX ELISA Kits
Peroxiredoxins (PRDXs) are a family of antioxidant enzymes that play a crucial role in reducing hydrogen peroxide and organic hydroperoxides, thereby protecting cells from oxidative damage. Quantifying PRDX levels in biological samples is essential for understanding their function in various physiological and pathological processes. Enzyme-Linked Immunosorbent Assay (ELISA) kits are widely used for this purpose due to their specificity and sensitivity.
Available PRDX ELISA Kits:
- PRDX3 (Peroxiredoxin-3) ELISA Kits:
- Assay Genie: Offers a Human PRDX3 ELISA Kit with high sensitivity, suitable for measuring PRDX3 in serum, plasma, and cell lysate samples.
- MyBioSource: Provides a Human Peroxiredoxin 3 (PRDX3) ELISA Kit with a detection range of 3.12 ng/mL to 200 ng/mL and a sensitivity up to 0.6 ng/mL.
- LSBio: Their Human PRDX3 / Peroxiredoxin 3 Quant ELISA Kit is a 96-well sandwich ELISA capable of detecting PRDX3 down to 0.312 ng/mL in plasma and serum samples.
- PRDX4 (Peroxiredoxin-4) ELISA Kits:
- RayBiotech: Provides a Human Peroxiredoxin-4/PRDX4 ELISA Kit for quantitative measurement in serum, plasma, and cell culture supernatants.
- Aviva Systems Biology: Offers a Human PRDX4 / Peroxiredoxin-4 ELISA Kit based on a standard sandwich ELISA technology, suitable for various biological fluids.
Applications:
PRDX ELISA kits are instrumental in research areas such as:
- Oxidative Stress Studies: Assessing PRDX levels helps in understanding cellular responses to oxidative stress and the role of antioxidants in mitigating damage.
- Cancer Research: PRDXs are implicated in tumor progression and resistance to therapy; quantifying their expression can provide insights into cancer biology.
- Neurodegenerative Diseases: Investigating PRDX expression aids in exploring mechanisms underlying diseases like Alzheimer's and Parkinson's, where oxidative stress is a contributing factor.
- Inflammatory Disorders: PRDXs modulate inflammatory responses; their measurement can elucidate their role in conditions such as arthritis and cardiovascular diseases.
When selecting a PRDX ELISA kit, consider factors like specificity for the PRDX isoform of interest, sample compatibility, sensitivity, and detection range to ensure it aligns with your research objectives.
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