SEPT ELISA Kits

SEPT ELISA Kits are specialized immunoassays developed for the quantification of septin (SEPT) proteins in biological samples. Septins are a family of GTP-binding proteins involved in various cellular processes, including cytokinesis, cell division, vesicle trafficking, and cytoskeletal organization. Due to their role in cell structure and function, septins are implicated in multiple diseases, including cancer, neurodegenerative disorders, and infectious diseases.

Content:

SEPT ELISA Kits typically include antibodies specific to one or more septin family members (e.g., SEPT2, SEPT5, SEPT7), ensuring high specificity and sensitivity. These kits provide pre-coated plates, detection antibodies, assay buffers, calibration standards, and substrates, making them suited for quantitative measurement of SEPT proteins in complex biological samples like serum, plasma, tissue extracts, and cell lysates. 

Applications:

• Cancer Research: Aberrant expression of septins has been linked to tumorigenesis and metastasis in various cancers. SEPT ELISA Kits enable the quantification of specific septins involved in cancer cell division and migration, aiding in studies of tumor growth, invasion, and metastasis. These kits are used to evaluate the impact of anti-cancer treatments targeting septin pathways and to identify septin biomarkers for cancer diagnosis and prognosis.
• Infectious Disease and Host-Pathogen Interaction: Certain pathogens exploit septins for cell entry, replication, or escape. SEPT ELISA Kits are valuable for studying the role of septins in infections, such as bacterial or viral pathogens that manipulate host septin networks. This helps researchers understand mechanisms of infection and develop therapeutic strategies to counteract pathogen exploitation of host cells.
• Reproductive Biology: Septins are also involved in reproductive cell division, such as in meiosis and gametogenesis. SEPT ELISA Kits facilitate studies on reproductive health and infertility, allowing for the assessment of septin expression in reproductive tissues and their influence on cellular functions during gamete formation.

SEPT ELISA Kits provide a precise, quantitative means to study septin proteins across various research areas. By enabling the accurate measurement of these multifunctional proteins, SEPT ELISA Kits support advancements in cancer research, neurobiology, cell biology, infectious disease, and reproductive health.