Transthyretin ELISA Kits

Transthyretin (TTR), also known as prealbumin, is a transport protein primarily synthesized in the liver and choroid plexus. It plays a crucial role in the transport of thyroxine (T4) and retinol-binding protein bound to retinol (vitamin A). Abnormal levels of TTR are associated with various clinical conditions, including malnutrition, liver dysfunction, and amyloid diseases such as familial amyloid polyneuropathy and senile systemic amyloidosis.

Key Features:

  • Sensitivity and Specificity: Designed to detect low concentrations of TTR with high specificity, minimizing cross-reactivity with similar proteins.
  • Assay Range: Typically, these kits offer a detection range suitable for physiological and pathological levels of TTR. For example, the Human TTR ELISA Kit from Assay Genie has a detection range of 0.312–20 ng/mL with a sensitivity of 0.188 ng/mL. Assay Genie
  • Sample Types: Validated for use with various sample matrices, including serum, plasma, cerebrospinal fluid (CSF), tissue homogenates, and cell culture supernatants, providing versatility for different research needs.
  • Assay Time: The total assay duration varies but generally ranges from 1 to 5 hours, facilitating efficient processing of multiple samples.

Applications:

  • Clinical Diagnostics: TTR levels are used as a biomarker for nutritional status, particularly in assessing protein-energy malnutrition. Low TTR levels may indicate malnutrition or liver dysfunction, while elevated levels can be associated with inflammation or renal dysfunction.
  • Amyloidosis Research: Mutations in the TTR gene can lead to amyloid fibril formation, resulting in conditions such as familial amyloid polyneuropathy and senile systemic amyloidosis. TTR ELISA kits are utilized to study TTR levels and their role in amyloid diseases.
  • Pharmacological Research: In drug development, TTR levels serve as biomarkers to evaluate the efficacy of therapeutic agents targeting TTR-related amyloidosis. Monitoring TTR can help determine the impact of therapeutic interventions aimed at stabilizing TTR and preventing amyloid fibril formation.

By providing accurate quantification of TTR levels, these ELISA kits are invaluable tools in clinical diagnostics and biomedical research, facilitating studies on nutritional status, amyloid diseases, and the efficacy of therapeutic interventions.

AffiELISA® Porcine Transthyretin | TTR | ELISA Kit
CAT# AFG-SM-14955
Size: 96 Wells
536.00 536.0 USD
AffiELISA® Goat Transthyretin | TTR | ELISA Kit
CAT# AFG-SM-13484
Size: 96 Wells
536.00 536.0 USD
536.00 536.0 USD
AffiELISA® Chicken Transthyretin | TTR | ELISA Kit
CAT# AFG-SM-10544
Size: 96 Wells
536.00 536.0 USD
AffiELISA® Canine Transthyretin | TTR | ELISA Kit
CAT# AFG-SM-08967
Size: 96 Wells
536.00 536.0 USD
AffiELISA® Bovine Transthyretin | TTR | ELISA Kit
CAT# AFG-SM-06866
Size: 96 Wells
536.00 536.0 USD
AffiELISA® Mouse Transthyretin | TTR | ELISA Kit
CAT# AFG-SM-04822
Size: 96 Wells
536.00 536.0 USD
AffiELISA® Rat Transthyretin | TTR | ELISA Kit
CAT# AFG-SM-03884
Size: 96 Wells
513.00 513.0 USD
AffiELISA® Human Transthyretin | TTR | ELISA Kit
CAT# AFG-SM-02111
Size: 96 Wells
490.00 490.0 USD
AffiELISA® Rat transthyretin | TTR | ELISA Kit
CAT# AFG-SB-7382
Size: 96 Wells
592.00 592.0 USD
AffiELISA® Human transthyretin, TTR ELISA Kit
CAT# AFG-SB-4134
Size: 96 Wells
490.00 490.0 USD
454.00 454.0 USD
454.00 454.0 USD
454.00 454.0 USD
389.00 389.0 USD
389.00 389.0 USD
389.00 389.0 USD
AffiELISA® Rat Transthyretin, TTR ELISA Kit
CAT# AFG-YBE-10173
Size: 96 Wells
310.00 310.0 USD
AffiELISA® Rabbit Transthyretin, TTR ELISA Kit
CAT# AFG-YBE-08529
Size: 96 Wells
310.00 310.0 USD
AffiELISA® Porcine Transthyretin, TTR ELISA Kit
CAT# AFG-YBE-08236
Size: 96 Wells
323.00 323.0 USD
AffiELISA® Mouse Transthyretin, TTR ELISA Kit
CAT# AFG-YBE-07674
Size: 96 Wells
310.00 310.0 USD
AffiELISA® Human transthyretin, TTR ELISA Kit
CAT# AFG-YBE-05695
Size: 96 Wells
282.00 282.0 USD
AffiELISA® Chicken Transthyretin, TTR ELISA Kit
CAT# AFG-YBE-01033
Size: 96 Wells
343.00 343.0 USD
AffiELISA® Bovine Transthyretin, TTR ELISA Kit
CAT# AFG-YBE-00390
Size: 96 Wells
323.00 323.0 USD
AffiELISA® Human Transthyretin (TTR) ELISA Kit
CAT# AFG-DDP-1318
Size: 96 Tests
616.00 616.0 USD
AffiELISA® Mouse Transthyretin (TTR) ELISA Kit
CAT# AFG-DDP-1681
Size: 96 Tests
631.88 631.88 USD
AffiELISA® Rat Transthyretin (TTR) ELISA Kit
CAT# AFG-DDP-2969
Size: 96 Tests
663.30 663.3000000000001 USD
AffiELISA® Porcine Transthyretin (TTR) ELISA Kit
CAT# AFG-DDP-5584
Size: 96 Tests
726.15 726.15 USD
AffiELISA® Bovine Transthyretin (TTR) ELISA Kit
CAT# AFG-DDP-5583
Size: 96 Tests
726.15 726.15 USD
AffiELISA® Transthyretin ELISA kit
CAT# AFG-BGE-8331
Size: 96 Tests
747.50 747.5 USD